Misiones Province Vacations & Trips from $295

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Your Misiones Province Vacation

See and do more with a Misiones Province vacation package. Whether you're going for its fishing, walking trails, watersports, or something else, our package deals make travel planning a breeze. Your trip to Misiones Province wouldn't be complete without exploring its best cities, starting with Posadas, Puerto Libertad and Puerto Rico. Whether you're traveling for a couple of days or a couple of weeks, Expedia are here to help you tailor-make your next Misiones Province vacation.

Top destinations in Misiones Province

A large waterfall with multiple tiers, surrounded by lush greenery and a viewing platform with people observing.

Puerto Iguazú

Puerto Iguazú
A natural rock arch formation in turquoise waters with a mountainous backdrop.

Posadas

Posadas
A large waterfall with a boat in the middle of the river.

Puerto Libertad

Puerto Libertad
Ancient brick ruins with columns and intricate carvings.

San Ignacio

San Ignacio

The Latest Misiones Province Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Iguazú Grand Hotel

Iguazú Grand Hotel

Save 100% on your flight
$295
per person
Dec 23 - Dec 25
found 1 day ago
Roundtrip flight included
Buenos Aires (BUE) to Iguazu (IGR)
9.2/10 Wonderful! (682 reviews)
Gran Melia Iguazú

Gran Melia Iguazú

$606
per person
Dec 3 - Dec 5
found 2 hours ago
Roundtrip flight included
Buenos Aires (AEP) to Iguazu (IGR)
9.4/10 Exceptional! (1,003 reviews)
Beautiful hotel that is convenient for visiting Iguazu Falls Argentina. Most of the staff is helpful and friendly. We had dinner, breakfast and lunch at the hotel. The food was really good but the head waitstaff at dinner & lunch were standoffish and less friendly that expected from a tourist location.

Reviewed on Oct 4, 2026

Selvaje lodge Iguazu

Selvaje lodge Iguazu

Save 100% on your flight
$353
per person
Dec 23 - Dec 25
found 1 day ago
Roundtrip flight included
Buenos Aires (BUE) to Iguazu (IGR)
9.2/10 Wonderful! (401 reviews)
Great stay! Food was good …. We’re not as helpful and friendly….

Reviewed on Sep 14, 2026

Reserva Natural Iguazú - Pristine Luxury Camp

Reserva Natural Iguazú - Pristine Luxury Camp

Save 100% on your flight
$449
per person
Dec 15 - Dec 17
found 24 hours ago
Roundtrip flight included
Buenos Aires (BUE) to Iguazu (IGR)
9.4/10 Exceptional! (6 reviews)
Loi Suites Iguazú Hotel

Loi Suites Iguazú Hotel

Save 100% on your flight
$439
per person
Dec 23 - Dec 25
found 1 day ago
Roundtrip flight included
Buenos Aires (BUE) to Iguazu (IGR)
9.2/10 Wonderful! (1,001 reviews)
A super location in a superb environment. This hotel has seen better days and it could do with an upgrade, it feels a bit 90s, especially the spa, and the in-room facilities. Definitely a nice place, but if I was the owner, I would invest a bit more, so I could remain competitive. Too many excellent hotels in the area to choose from.

Reviewed on Sep 27, 2026

Where to stay in Misiones Province

Find the best Misiones Province areas and neighborhoods for the activities you enjoy most.Learn more about Misiones Province
Learn more about Misiones Province

Downtown Iguazú

The abundant dining options and secluded waterfalls are top of the list for many visitors to Downtown Iguazú. A stop by Plaza San Martin or Café Central Casino might round out your trip.

Zona Granja

Visitors to Zona Granja enjoy its waterfalls, and if you want to do some exploring, La Aripuca is worth a stop.

Comandante Andresito

If you're looking for some top things to see and do in Comandante Andresito and surrounding area, you can visit Iguazu Casino and Duty Free Shop Puerto Iguazu.

Villa Tacuara

While there might not be top attractions in Villa Tacuara, you can explore the larger area and discover places like Iguazu Casino and Hummingbird Garden.

Santa Maria de Iguazú

While Santa Maria de Iguazú might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Iguazu Casino and Duty Free Shop Puerto Iguazu.

Best Places to Vacation in Misiones Province

1. Enjoy Puerto Iguazú with a travel package

Puerto Iguazú in Misiones Province, Argentina offers a unique and diverse outdoor vacation experience. With its stunning waterfalls, lush jungles, and scenic hiking trails, nature lovers will be in paradise. The area is also perfect for romantic getaways and wildlife enthusiasts, with opportunities for hunting and observing exotic animals. Adventure seekers can enjoy thrilling tours and activities, while those looking for a more relaxed experience can explore the rainforest at their own pace. Additionally, Puerto Iguazú offers shopping tours and sightseeing opportunities, ensuring there is something for everyone in this vibrant destination.

  • Travelers tend to stay 3 days in Puerto Iguazú

2. Create memories in Posadas with a vacation package

Posadas, located in the Misiones Province of Argentina, offers a unique outdoor vacation experience. With its stunning natural beauty, visitors can indulge in activities such as spa treatments, waterskiing, exploring ancient ruins, and enjoying the picturesque river views. The city is also known for its trendy atmosphere and delicious seafood, which can be savored while boating on the river or sipping coffee at local cafes. For those seeking spiritual solace, Posadas boasts beautiful churches. Additionally, swimming in the refreshing waters of the region is a popular pastime. Whether you're exploring the outdoors or immersing yourself in local culture, Posadas has something for everyone.

  • The peak season is from December to February
  • The off-peak season is from March to May
  • Travelers tend to stay 2 days in Posadas

3. Find your perfect Puerto Libertad vacation

Puerto Libertad in Misiones Province, Argentina, offers an exceptional outdoor vacation experience. With its family-friendly atmosphere, it is perfect for a getaway with your loved ones. The lush jungles and rainforests surrounding the area provide a stunning backdrop for exploration and adventure. You can immerse yourself in the beauty of nature, discover breathtaking waterfalls, and indulge in delicious dining experiences. Puerto Libertad truly offers something for everyone, whether you seek a romantic retreat or an exciting family vacation.

  • The peak season is from February to April
  • The off-peak season is from August to October
  • Travelers tend to stay 2 days in Puerto Libertad

4. Experience Obera with a travel package

Obera, located in the Misiones Province of Argentina, offers a fantastic atmosphere for a family vacation. With its natural parks, theme parks, spas, and adventurous activities, there's something for everyone to enjoy. Explore the beautiful landscapes and immerse yourself in the local culture. Take a cruise or an ocean cruise to experience the region's waterways and marine life. Obera is a perfect destination for families seeking both relaxation and excitement. Whether you're exploring the natural wonders or enjoying thrilling activities, Obera promises a memorable vacation experience for the whole family.

  • The peak season is from July to September
  • The off-peak season is from March to May
  • Travelers tend to stay 1 day in Obera

6. Book your ideal Comandante Andresito with a vacation package

San Ignacio, located in the Misiones Province of Argentina, offers a unique cultural vacation experience. With its picturesque landscapes and friendly people, the town is perfect for exploring gardens, swimming, and visiting historical monuments. Immerse yourself in the local atmosphere by participating in destination activities, tours, and sightseeing. Don't miss the opportunity to visit the aquarium and zoo, which offer a chance to see diverse wildlife. Whether you're looking for a relaxing getaway or an adventure-filled vacation, San Ignacio has something for everyone.

  • The peak season is from July to September
  • The off-peak season is from April to June

5. Escape to San Ignacio with a vacation package

Dos de Mayo, located in Misiones Province, Argentina, offers an incredible outdoor vacation experience. Immerse yourself in the lush greenery of the surrounding rainforests, where you can explore nature trails, spot exotic wildlife, and marvel at breathtaking waterfalls. The warm and welcoming local atmosphere invites you to discover the rich culture and traditions of the region. Enjoy outdoor activities such as hiking, birdwatching, and fishing, or simply unwind and soak in the natural beauty. Dos de Mayo provides a serene and rejuvenating escape, perfect for those seeking an unforgettable outdoor adventure.

  • The peak season is from December to February
  • The off-peak season is from April to June
  • Travelers tend to stay 1 day in San Ignacio

Find the Best Misiones Province Vacation Packages

Misiones Province Essential Information

Language
Spanish
Currency
Argentine pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Cataratas del Iguazu Intl. Airport (IGR)
Top Sights
Iguazu National Park, Hummingbird Garden and Jardin de los Picaflores

Misiones Province Hotel Deals

Gran Melia Iguazú

Gran Melia Iguazú

Parque Nacional Iguazu Puerto Iguazú Misiones
Fully refundableReserve now, pay when you stay
$828 nightly
$837 total
Oct 19 - Oct 20
9.4/10 Exceptional! (1,003 reviews)
"Beautiful hotel that is convenient for visiting Iguazu Falls Argentina. Most of the staff is helpful and friendly. We had dinner, breakfast and lunch at the hotel. The food was really good but the head waitstaff at dinner & lunch were standoffish and less friendly that expected from a tourist ..."

Reviewed on Oct 4, 2026

Gran Melia Iguazú
Hotel Saint George

Hotel Saint George

Avenida Cordoba 148 Puerto Iguazú Misiones
Fully refundableReserve now, pay when you stay
$137 nightly
$144 total
Oct 6 - Oct 7
9/10 Wonderful! (1,003 reviews)
"Great place to stay, everything is clean, breakfast is amazing, especially the fresh juice and fruits. Thanks"

Reviewed on Oct 3, 2026

Hotel Saint George
Loi Suites Iguazú Hotel

Loi Suites Iguazú Hotel

Selva Iriapu Sin Numero Puerto Iguazú Misiones
Fully refundableReserve now, pay when you stay
$380 nightly
$389 total
Oct 14 - Oct 15
9.2/10 Wonderful! (1,000 reviews)
"A super location in a superb environment. This hotel has seen better days and it could do with an upgrade, it feels a bit 90s, especially the spa, and the in-room facilities. Definitely a nice place, but if I was the owner, I would invest a bit more, so I could remain competitive. Too many excellent ..."

Reviewed on Sep 27, 2026

Loi Suites Iguazú Hotel
See all 404 properties in Misiones Province
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Misiones Province vacation package cost?
Vacation packages in Misiones Province are centered on Puerto Iguazú. A weekend trip there typically costs around $550 per adult, with prices ranging from around $300 to $1,250 per adult.*Package prices shown are the average total cost per adult across Expedia bookings over the past year and may change depending on availability, dates, and demand.
How can I save money on a Misiones Province vacation package?
When you bundle, you can save up to 30%*. To save money on a Misiones Province package, consider traveling during the quieter months or be flexible with your dates to find more options. Bundling your flights and hotel together often unlocks savings compared to booking separately. *Members only. Savings vary.
What's included in a Misiones Province vacation package?
A Misiones Province vacation package in Puerto Iguazú lets you combine flights, hotel stays, and rental cars. Most hotels in Puerto Iguazú offer free breakfast, and most also provide airport shuttle service.Exactly what's included will vary by hotel and package, so it's worth reviewing the details before you confirm your booking.
How do I find cheap Misiones Province vacation package deals?
Lower-priced Misiones Province vacation packages are available in Puerto Iguazú, where prices start around $270 per adult for weekend trips. Package prices in December average around $490 per adult for a 2-day trip.Bundling your flight and hotel can offer additional savings compared with booking separately. Week-long Puerto Iguazú packages typically save around $60 per adult.Browse cheap vacation packages in Misiones Province on Expedia to compare current deals for Puerto Iguazú and your travel dates.*Package prices shown are the average total cost per adult across Expedia bookings over the past year and may change depending on availability, dates, and demand.
What is the best time to visit Misiones Province?
The best time for a Misiones Province vacation package in Puerto Iguazú is November through March, when highs are around 87°F to 89°F. This period aligns with the peak booking months for the area, offering a lively atmosphere. Conditions may differ in other parts of the province.If you prefer a quieter trip with fewer crowds, consider visiting in July or September. During these months, highs are milder, around 72°F to 82°F, providing comfortable weather for exploring.
What types of vacation packages are available in Misiones Province?
Misiones Province vacation packages, concentrated in Puerto Iguazú, come in several travel styles:
  • Budget: About half of the hotels in Puerto Iguazú fall into the budget tier, with options like Poramba Hostel, rated 8.8 out of 10 by travelers, offering amenities such as an outdoor pool and free WiFi.
  • Breakfast: Many packages include breakfast, with properties like the 5-star Entre Arboles Iguazu, Singular Collection by Amerian, rated 9.8 out of 10 by travelers, providing free breakfast, a restaurant, and a spa.
  • Couples: For a romantic escape, consider packages with stays at hotels like the 5-star Gran Melia Iguazú, rated 9.2 out of 10 by travelers, which features an outdoor pool and spa, and is praised for its amazing views.
  • Family: Family-friendly packages often include stays at resorts such as the 5-star Loi Suites Iguazú Hotel, rated 8.7 out of 10 by travelers, which offers family rooms, a kids club, and a playground, with travelers highlighting the great staff and amazing pool.
  • Luxury: Indulge in luxury with options like the 5-star Overo Lodge & Selva, rated 8.9 out of 10 by travelers, providing an outdoor pool, restaurant, and spa, with travelers noting the amazing overall experience and comfortable rooms.
Which destinations should I consider for a Misiones Province vacation?
When planning a Misiones Province vacation, consider these destinations as your base, each offering a different travel experience:
  • Puerto Iguazú: This is a strong base for travelers seeking adventure activities, outdoor exploration, and family-friendly attractions, with many lodging choices available.
  • Posadas: For those interested in cultural attractions and urban experiences, Posadas offers a city-focused stay with family-friendly options.
  • El Soberbio: Couples looking for a romantic getaway with outdoor activities and a focus on wellness and relaxation will find El Soberbio appealing.
  • Obera: Families can enjoy Obera for its family-friendly attractions, outdoor activities, and eco-friendly travel opportunities.
Is Misiones Province better suited for a beach vacation or a cultural trip?
Misiones Province is primarily an outdoor and nature destination, known for adventure activities and scenic views. Its lush landscapes and natural wonders, such as the Iguazu Falls, are central to the experience.The province does offer some beach experiences, like San Jose Beach in Posadas. It also boasts a rich cultural history, particularly with the Jesuit Reductions like San Ignacio Miní, which were established in the 17th century and offer a glimpse into the region's past.Overall, a Misiones Province vacation is best for travelers seeking outdoor adventure and natural beauty, complemented by significant historical and cultural exploration.
Which airport should I use for a Misiones Province vacation?
For a Misiones Province vacation, you have a few airport options depending on your destination within the region. If your package is centered around Puerto Iguazú and the famous Iguazu Falls, you can fly into Iguassu Falls (IGU-Foz do Iguacu Intl.) or Iguazu (IGR-Cataratas del Iguazu Intl.). For packages to the provincial capital, Posadas, consider flying into Posadas (PSS-Libertador General Jose de San Martin).
What are the top things to do in Misiones Province?
A Misiones Province vacation is best explored from a base like Puerto Iguazú, which offers access to some of the region's most iconic sights:Browse and book things to do in Misiones Province on Expedia.
What is the best time to book a Misiones Province vacation package?
Book your Misiones Province vacation package around 6 weeks in advance, with packages located in Puerto Iguazú. Most travelers book between 2 and 14 weeks out. It gives you time to secure your preferred flights and hotel while rates are still competitive.March, November, and December are the most popular months for Misiones Province packages in Puerto Iguazú, so booking earlier is advisable if you're traveling during those months.
How many days do you need for a Misiones Province vacation?
Most Misiones Province vacation packages last around 2 days, with stays in Puerto Iguazú, a destination known for outdoor and adventure activities. Nearly all travelers choose weekend trips, while some opt for week-long stays to explore more deeply. This allows time to experience attractions like Iguazu Falls.
Can I change or cancel my Misiones Province vacation package if my plans change?
Yes, you can cancel your vacation package via your itinerary page on Expedia or by contacting customer service. Remember that some packages are fully refundable, but the details vary based on each unique booking. A fully refundable package may depend on how far out from the travel dates you're canceling and what airline you are traveling with.
Do One Key members get extra savings when booking Misiones Province vacation packages?
Yes, members who join our free One Key™ travel rewards program can instantly unlock additional savings and save 10% or more on over 500,000 stays worldwide with Member Prices and over 1 million car rentals.
Does Expedia offer Book Now, Pay Later Misiones Province vacation packages?
Yes, with Expedia's Book Now, Pay Later option, powered by Affirm, you can spread the cost of your Misiones Province vacation over 3, 6, or 12 months. With no late payment fees or hidden costs, it's easy to secure your ideal vacation package as soon as you spot it.
How do I find last-minute vacation packages to Misiones Province?
To find last-minute vacation packages to Misiones Province, explore the last-minute deals section for the latest package offers, including flights, departing in the coming weeks. Being flexible with your travel dates and hotel preferences can help you secure the best prices.
How does free cancellation work on Misiones Province vacation packages?
Free cancellation on a Misiones Province vacation package depends on the specific hotel and rate combination you book. Many bookings allow free cancellation up to a stated deadline (often a few days before travel) where eligible. Read the cancellation terms carefully when reviewing the package, and visit Expedia help center for further details.
Is it cheaper to book a Misiones Province vacation as a package or separately?
Booking flights and hotels together can unlock lower overall prices. Better still, you can tailor your Misiones Province getaway to match your exact preference. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
Why should I book my Misiones Province vacation package with Expedia?
Booking your vacation package on Expedia makes it easier to get more out of your trip from the start. With a wide choice of hotels, you can compare prices, reviews and amenities all in one place, then bundle your hotel with flights which could help you save even more. Flexible booking options on selected stays also make it easier to plan with confidence.

Stay near popular Misiones Province attractions

A river flanked by lush green hills, a bridge, and a house on a hill.

Triple Frontier

8.8/10 (248 reviews)
Find out about the history of Puerto Iguazú with a stop at Triple Frontier. Discover the area's beautiful waterfalls, or seek out its local tours.
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A river with a waterfall surrounded by dense green forest and a cloudy sky.

Port

8.4/10 (28 reviews)
After visiting Port, make a plan to see the other sights and activities in Puerto Iguazú. Discover the area's beautiful waterfalls, or seek out its local tours.
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Ancient brick ruins with columns and intricate carvings.
Photo by Mark Rentz

San Ignacio Miní

8.2/10 (13 reviews)
Find out about the history of San Ignacio when you spend time at San Ignacio Miní. Amble around the area's gardens or visit its monuments.
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A hummingbird perched on a colorful bird feeder with red, blue, and yellow flowers.

Hummingbird Garden

8.2/10 (66 reviews)
Explore the lovely green spaces of Hummingbird Garden and also enjoy the hiking trails in Puerto Iguazú. Discover the area's beautiful waterfalls, or seek out its local tours.
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Duty Free Shop Puerto Iguazu

7.8/10 (100 reviews)
You can search for that perfect souvenir at Duty Free Shop Puerto Iguazu during your stay in Puerto Iguazú. Discover the beautiful waterfalls in this romantic area, or enjoy its local tours.
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Iguazu Casino

7.8/10 (83 reviews)
Why not try your luck with a visit to Iguazu Casino during your visit to Puerto Iguazú? Amble around the area's scenic parks or seek out the local tours.
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Argentina-Paraguay Bridge

7.0/10 (41 reviews)
You can learn about the history of Posadas when you stop by Argentina-Paraguay Bridge. Stroll along the riverfront or visit the spas while you're in the area.
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Iryapu Forest

9.0/10 (4 reviews)
Enjoy the beautiful waterfalls and explore Iryapu Forest, a lovely green space in Puerto Iguazú. Wander the area's lush forest or simply enjoy one of its top-notch restaurants.
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What to do in Misiones Province

Private Tour 1-2 Day Tour: Both sides of the Iguazu Falls

Private Tour Iguazu Falls, Brazil & Argentina

$162
per adult
Private Tour Iguazu Falls, Brazil & Argentina
Full Day Iguassu Falls Both Sides -Argentina and Brazil

Small group Falls Both Sides - Argentina and Brazil

$49
per adult
100% of travellers recommend
Small group Falls Both Sides - Argentina and Brazil
Iguazu Falls: 2-Day Argentinian and Brazilian Iguazu Falls

Iguazu Falls: 2-Day Argentinian and Brazilian Iguazu Falls

$49
per adult
Iguazu Falls: 2-Day Argentinian and Brazilian Iguazu Falls
See all activities in Misiones Province
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.